CCR5:
Cell surface molecule, which is needed along with the primary receptor, the CD4 molecule, in order to fuse with the membranes of the immune system cells. Researchers have found that the strains of HIV most often transmitted from person to person require the CCR5 molecule and CD4 molecule in order for HIV to enter the cell. In addition to its role in fusion, CKR5 is a receptor for certain immune-signaling molecules called chemokines that are known to suppress HIV infection of cells. See Chemokines; CXCR4.
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