Gp120 (Gp120):
(gp120.) Glycoprotein 120, a protein that protrudes from the surface of HIV and binds to CD4+ T cells. In a two-step process that allows HIV to breach the membrane of T cells, gp120-CD4 complex refolds to reveal a second structure that binds to CCR5, one of several chemokine co-receptors used by the virus to gain entry into T cells.
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