Alzheimer's Disease
Chronic Fatigue Syndrome
Deafness / Communication Disorders
Dental Terms
Depression Terms
Diabetes Terms
Digestive Disease
Eye Terms
Health Resources
Heart Terms
Medical Terms
Mental Health Terms
Rare Diseases
STD Terms
Surgery Terms
Health & Medical Patents

Phase I Trials:

Involve the initial introduction of an investigational new drug into humans. Phase I trials are closely monitored and may be conducted in patients or in healthy volunteers. The studies are designed to determine the metabolism and pharmacologic actions of the drug in humans, safety, side effects associated with increasing doses, and if possible, early evidence of effectiveness. The trials also can include studies of structure-activity relationships, mechanisms of action in humans, use of the investigational drug as research tools to explore biological phenomena, or disease processes. The total number of patients included in Phase I studies varies but is generally in the range of 20 to 80. Sufficient information should be obtained in the trial to permit design of well-controlled, scientifically valid Phase II studies.

More AIDS / HIV Terms

# | A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z

Information and definitions of the medical conditions and diseases have been taken from various reliable government publications and we have done our best to verify their accuracy. If you feel any of the definitions are incorrect or needs to be updated please contact us and we will look into it.