Structured Treatment Interruption (Sti):

STI is the planned interruption of treatment by discontinuation of all antiretroviral drugs. There are four reasons to consider STI (1) to provide a "drug holiday" to patients to relieve them of the inconvenience and toxicity of unsuccessful antiretroviral therapy and to improve the response to salvage therapy by allowing the emergence of wild-type virus; (2) to "re-immunize" the patient to HIV in the hopes of regaining immunologic control through a regenerated HIV-specific immune response; (3) to decrease the cumulative exposure to antiretroviral agents, reducing toxicity and cost and improving quality of life; and (4) to discontinue antiretroviral drugs during the first trimester of pregnancy.

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Information and definitions of the medical conditions and diseases have been taken from various reliable government publications and we have done our best to verify their accuracy. If you feel any of the definitions are incorrect or needs to be updated please contact us and we will look into it.

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